Guide
How Much Do Polynucleotides Cost in the UK?
Polynucleotide injectables in the UK are commonly advertised around £175–£450 per session, with three-session facial courses often £550–£650. Under-eye protocols may sit at the lower end. General market guidance — not Modelow prices.
Polynucleotide price overview
Pricing varies by brand (Plinest, Nucleofill, Ameela etc.), area and course length. Prices below reflect advertised UK clinic menus reviewed in September 2026 — not Modelow prices.
General UK market guidance — not Modelow prices
| Typical UK pricing | Guide range |
|---|---|
| Face — single session | Commonly around £175–£300Lír Aesthetics from £175; ZOLU £250; Eternal Glow £220. |
| Under-eye / periorbital | Commonly around £175–£250 per sessionEye area is a common entry point; often priced at lower end of range. |
| Course of 3 (face) | Commonly around £550–£650ZOLU £650; Eternal Glow £550; Lír Aesthetics up to £450 per session tier. |
| Course of 2 | Commonly around £400–£495Eternal Glow 2-session package £400; Radiant Living neck £495 for 2. |
| Neck | Commonly around £240–£450 per sessionRadiant Living neck single £240; combined face/neck courses cost more. |
| Scalp / hair polynucleotides | Commonly around £250–£450 per sessionHair indication priced separately on some clinic menus. |
What affects the price
Brand and formulation
Plinest, Nucleofill, Ameela, Newest and other brands are priced differently.
Treatment area
Under-eye sessions often cost less than full-face or neck-décolletage combinations.
Course length
Most clinics recommend 2–4 sessions spaced 2–4 weeks apart for skin quality results.
Combination with other injectables
Some clinics bundle polynucleotides with skin boosters or Profhilo at package rates.
Practitioner and location
London doctor-led clinics typically sit above regional independent menus.
Why can Modelow appointments cost less?
Some clinics offer reduced-price appointments when they need a model for training, demonstrations, content or supervised practice. The lower price reflects the appointment type — not necessarily lower standards.
Prices change and differ between clinics. Confirm the exact treatment, practitioner, inclusions and total cost before you book.
Sources: Advertised UK clinic prices reviewed September 2026 (8 providers). Research date: September 2026.
Brand and formulation differences
Different polynucleotide brands are priced differently on clinic menus. Confirm which product you are receiving — Plinest, Nucleofill and Ameela are not interchangeable.
Frequently asked questions
- Are polynucleotides cheaper than Profhilo?
- Entry-level polynucleotide sessions can be slightly cheaper than Profhilo on some menus, but total course cost depends on sessions required and brand selected.
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